Another thing - don't overdo the gifts to kids, as after a while they start taking them for granted/seeing them as payment. If you can't take the family with you, send them postcards - kids get a thrill out of receiving mail addressed to themselves, & you can always find a story that a five year old will appreciate.
During my most intense period of travelling (over 50000 miles in ~3 months) I lived in a different country from my partner, which may have made things easier. We made a point of taking a long weekend alone together every month or three weeks, & every two or three months we'd meet in a third country & do some travelling together. Earthbound partners often feel left out.
I can't envisage trying to sustain that level of travelling for longer than 12 months: apart from the detrimental effect on one's personal life, the long flights are physically exhausting and spending fewer than two nights a week at home can lose its attraction.