My family and our best friends often go on holiday together. Most of the time 3 F seats with miles or upgraded and 3 paid biz seats usually used by the children.
For myself I take any good F or A (RTW) deal. Rest of flights on miles. Worked well so far and I am glad to be in such a fortunate situation.
If I could, I would take the Queen Mary 2 across the Atlantic in a Queen's Grill Suite.