I'm planning a trip from STL to Geneva (GVA) in a few weeks. There aren't a lot of great option for travel out of STL, but that's a different story.

There are a few ways to get to GVA:

Delta to JFK, SwissAir to GVA
Continental to EWR to GVA
AA/BA to ORD to LHR to GVA (LHR connection is T4 to T4)

Now, normally the fewer connections the better. BUT I've done the EWR connection, and it doesn't work well from here.

From STL, missing my EWR flight or getting stranded on the way back is significantly probable. There aren't all that many flights between STL and EWR. Last time I did this trip, I almost missed the flight going to EWR and was almost stranded in Newark for a couple of days on the return trip.

On the other hand, ORD is no picnic and I hear that LHR is miserable. But I'm tempted to do it. The ORD part doesn't worry me, as there are tons of flights and lots of other ways to get to my part of downstate IL from ORD and lots of local friends and relatives in Chicago. I'm used to ORD--the devil I know.

So, I'm asking you expert flyers: Given my aversion to EWR (YMMV), is it reasonable to book the ORD=>LHR=>GVA flight if I give myself reasonable connection times at ORD and LHR? My lack of knowledge of LHR compels me to ask the question.

(There's also the JFK option, but the STL to JFK connections are just as scarce as the STL to EWR options. At times, STL feels like the airport for a much smaller city!)

Thanks for any help or insights!