Originally Posted by billp

Most of the above suggestions are way above your budget. Here are a couple of comfortable hotels in my neighbourhood, which are within your budget ballpark and also meet your location criteria:

Hotel Jurine
and the Kastanienhof

Of the two, I would say the Jurine is nicer. It's a family-run hotel owned by a French fellow and his German wife. Both places are in Prenzlauer Berg...