No, but I did so in PDX in October with no problem (return portion of a round-trip, of course)

I attempted to do so with a 2-segment DL return in SFO last week, and the tkt agent indicated she would have done so, except that unfortunately I arrived late at the tkt counter.

Now the question is, can I do so internationally using my return tkt on CO: CDG-EWR-DTW , and instead travelling NW: CDG-DTW? We'll see.