There are a few threads that reference Santa Fe in this forum; you may want to check those out. As for driving between Albuquerque and Santa Fe, it is about an hour drive as silverthief2 has stated... in good weather.
Albuquerque, and New Mexico, in general, has been experiencing odd (snowy) weather closing I25 and I40. You may want to get to Santa Fe and stay there, or spend a few days there, and then a few days in Albuquerque to ensure you are able to get to ABQ.