I never ignore...but am perhaps overly neurotic when it comes to such matters. That reminds me that I need to review my stash when I get home.
The worst is dried spice. They really won't hurt you, but that's one thing people keep WAY too long. My dad has bottles in his spice cabinet that really have been there for at least 8 or 9 years, probably much more! I don't think he uses them, but I shudder to think... It's like pouring dirt on your chicken!