I stayed at the Melia Berlin at the end of October, just a few weeks after its opening.

It is indeed a very nice property. The location is very good, as it is just a half block from the Friedrichstrasse S-Bahn/U-Bahn station; in addition, Bus # 147 stops virtually at the door. Taxi connections will be easy to make.

The hotel fronts directly on Friedrichstrasse, along the Spree River. Museum Insel, the Brandenburg Tor and the Reichstag are very close by (my room, on the 5th floor, had a very nice view of the Reichstag's glass dome)

The decor is modern in warm, light earth tones and light woods, and the bed was very comfortable. Staff was warm and welcoming, The breakfast buffet was very good (if a tad pricey at 20 Euros) but the variety of foods offered was extensive (egs and hot dishes cooked to order). There is a tapas bar and full restaurant, but I did not try them.

From what I can tell, Melia prices the hotel ccouding to demand - I paid all of Eur. 73 for my room, however, the rate for the very next day was up to Eur. 110.

Beyond the Melia, I have stayed in the other hotels that USAFAN has listed, and they are all good options. For luxury at a price, the Regent (formerly the Four Seasons) is a good option, while the recently-opened Hotel de Rome is not (despite its stellar location).