Originally Posted by bkramt1
I live here and often take my luggage on the train with no probs. If staying downtown, an option would be to take the train into the city, drop the bags at the hotel, and then cab to United. If staying near the airport, drop bags first, then take the Blue Line in. The train is 45 minutes ORD to downtown, driving could be much more. Also consider the time it takes to rental shuttle and pick up / checkout rental car, too. Could be 2 hours and up.....
You can also just take the Forest Park Blue Line, get off at the Medical Center and walk to the UC.
The cost of the rental car + parking would outweigh the cab fares for the whole trip no doubt.