Absolutely practical. I've done it. Also did a two-nights-and-one-day trip to Santiago, with a full day in the city there. Overnight flight schedules from the U.S. in both directions make this a bit more practical than Paris, but you have one more day.

If you can get a late afternoon return flight on Sunday and are into that sort of thing, you might enjoy the traditional Latin mass at Notre Dame. There's a nearby RER station to get to CDG.

Only downside is you'll hate to leave that soon, but you probably know that.