It's Amsterdam because that's where it's easy for us to get to and, yes, that's where we're flying to. And we're committed to it now with hotel bookings.
The advice about doing less (eg. a couple of rooms in a museum or whatever) is a good point. My husband suspects that just sitting and watching the world go by in a different place to home will be something she'll enjoy.
The bus looks useful but I think for a short stay we may be as well to rely on taxis.
Thank you all for the advice. We go in about ten days time so hopefully the weather will be OK - that always helps!