I travel with a Costco 22" rroller and small computer portfolio (I'm downsizing every year -- learning to live with less). I'm a gadget guy but travel with the most compact accessories possible. (Flat Nike running shoes)
Advantages -- able to be flexible for bumps and certainly save time in possible lost / delayed luggage. I just got back from a week in Japan and am certainly glad I travelled light -- using the rail system daily etc. I don't know what I would have done with a large bag.