I have not had any meds/pills (prescription or otherwise) to help me deal w/jet lag flying east.

However for what it's worth: If I'm flying to Europe, it's usually a late afternoon/early evening/late evening flight, which takes you to your destination in the early morning local time. In this case I tend to start my day a bit earlier than usual (4/4:30a or even earlier), go abt my regular day, and make sure that by the time I'm seated in the a/c I'm pretty much done w/my day - the logic being - the more I tire myself out during the day, the easier it would be for me to sleep on the plane - and hence wake up fresh across the pond.

As for as flying to Asia is concerned....I'm yet to figure out a fool-proof way to deal w/jet lag, but I've found *not* sleeping on the first long leg flight (to Europe) and *sleeping* on the flight to your Asian destination *usually* helps....but not quite, since flights to Asia reach in the middle of the night(at least mine anyway) and I end up staying up all night to catch a domestic flight....but I'm still able to pull of the next day as a regular day and maybe sleep a bit earlier in the evening.........after that, no jet-lag

Just my experience. Not sure if it's even related to your post, since you were specifically asking abt pills.