<font face="Verdana, Arial, Helvetica, sans-serif" size="2">Originally posted by arnitaruiz:
Take the CalTrain. It is inexpensive and easy to use.</font>
IMO, probably not worth the trouble (walk to caltrain bus stop, wait for bus, take bus to caltrain station, wait for caltrain, take caltrain to embarcadero, cab to hotel) unless you happen to be arrive during the heart of the afternoon rush. I'd go for the cab option.