If I'm traveling for a day or two or three, I tend to carry on. If it will be longer, I tend to take a suitcase, as it really isn't that awful on domestic flights. The car service helps me with it if I'm tired or don't want to carry it.
I tend not to use the laundry service in hotels. They charge way too much, and do a half/half job, so I only get my suits cleaned if there is a spill or something.