I'm glad to know I'm not the only crazy person considering this. I know a lot of people do it for the Buffalo-Toronto stint, but if I recall correctly, that drive is closer to an hour, although I think the border crossing usually takes longer.
We have considered, and ruled out, the train. For a vacation of this length it just doesn't make sense and I think I might kill myself if I spent that long on the train, especially because every train I've ever been on in the US runs late except for the Acela!
Bummer there isn't anything interesting to see