Originally Posted by themicah
Note that there are two very different 757-200 models, the "755" (757-200 5500 series, which doesn't have any window exits, but has an extra set of full size exits) and the "756" (757-200 5600 series, which has two rows of window exits in lieu of the extra set of doors).
The config in FC is roughly the same on both, although the overhead bins are generally much larger on the 756. But in coach it's a different story.
I'd also generally recommend 2C/D. In fact, mrs. themicah and I are sitting there on a 756 in just a few hours!
This sort of information can generally be found at seatguru.com. Well maybe not overhead bin sizes. And certainly not the part about the themicahs' travel plans.