Same as OP -- work remotely for a software company, get the same re-imbursements, travel maybe 1/3 of the time. Haven't tried the HO deduction--and if you looked at my office, it definitely looks like it is used for more than work (I suppose I could fix that were there an audit).
The benefits of just being able to work in my boxers (on a cold day

) and essentially being able to make my own hours are such that I don't mind not getting the deduction (if it would go). It would be extremely difficult to have to go into an office again.
I may sing a different tune if I were self-employed (I think).