Great post! I find that the most luxurious hotels are the least convenient for a business traveler. On the other end of the continuum, I stay for about a week at a time at Staybridge Suites (I think they are a derivative of Holiday Inns). For a buck forty nine a night I get a suite with two rooms and a kitchen, a table large enough to work on, free highspeed internet, an Aeron chair . . .
In the nearby Hyatt, I have never been able to get in for less than two hundred per night and I am shoehorned into a single room with a desk (you guessed it) just like the OP describes. I am getting to the point where I am happy to stay in a newer Hilton Garden, Hampton Inn, Staybridge, Courtyard and so on. I will pass on the grand hotels when I am working.