All mentioned in earlier posts are great - Tony's, Tratoria Marcella, The Ritz, Harvest, the Crossing.

Another nice one is Sydney Street Cafe. It is in Soulard, near the Anheuser Busch Brewery. The menu changes nightly and is recited by the wait staff. It is diverse and the dishes are unique, but still something you want to eat.

The great thing about Sydney Street is that it is nice but not too stuffy for a college kid. The atmosphere is great.

You will need reservations and it is never too early to make them. Everyone I have ever taken there - work or family - has loved it.