As with Flying Mike, I fly three weeks out of each month from Phx on Am West. No horror stories in two years of doing so.
Average 3,000 miles per week; somewhere along the lines of 120,000 per year. Roughly 100k with Am West, a few SWA and a smattering of UA/AA/NW. Predominantly HH and Marriott family of hotels, 142 road nights last year and looking at 144 for 2001 if my schedule holds.