jebien There is little doubt that many are willing and able to help you. It is really impossible to answer your questions unless you give your departure city and/or mileage programs in which you are active. If you are not particularly faithful to one mileage program, than I suggest searching for all flights to Italy (assuming, you are USA-based) which offer discounted business fares. These are normally found as I fares or Z fares, depending on the airline and require an advance purchase fare as well as a minimum stay.
You can go to the individual airline websites; e.g.: AF, AZ,CO, DL, UA, AA, LH, etc., but you might be better-served by going to a more ubiquitious website such as Expedia. Again, there are many people on FT who could and would give you great information. We just need a little more input from you.
Welcome to FT.