Well, I'm sure you've done your research on the programs and primarily asking about domestic upgrades, but I think this is worth mentioning in case it isn't already on your radar.

If you're considering accruing on AA, then be aware of the wicked "copay" involved with redeeming your hard earned miles for upgrade internationally. It'll sure be a hit on your wallet that you're not used to taking for burning some miles on a intl-upgrade, amigo. It is the biggest downside to AAdvantage in my opinion, but since your travel patterns will be changing, I'm not sure how much you'll really care about this.

Upgrades From Most Discount Economy (Copay doesn't apply if you're flying Y or J):
North America to (Southern S America) 25,000 + $250
North America to Japan / Northern China 25,000 + $250
North America to Europe 25,000 + $250
North America to India 40,000 + $250

That is for each way. So a RT to Europe in business class would cost you your discount coach fare + $500 + 50,000 miles.

At least those eVIPs (sticker upgrades) don't require copays. Yet.

peace,
~Ben~

PS> Good luck with the new position!