When I am expecting weather problems on a flight I take Drammamine Less Drowsy as the previous poster suggested. It works for me, but you may need something stronger. Talk to your doctor about it. Even if you cannot get the patch any longer, there is a newer, oral scopalomine medication that is supposedly even better. One or two tablets for 8 hours. Prescription only.
Travel is too much fun to miss any of it feeling wretched. Your doctor should be able to help you.
JR