Yup, CO and others do it all the time

The two that come to mind first are IAH-EWR-PEK and in my case IAH-HNL-GUM, where the equipment actually does not change, but you have to get off the plane, and on the way back clear immigration / customs. And I'm not 100 percent sure, but belive it's CO to Hawaii and CO Micronesia from Hawaii to Guam
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