I heard this story third hand, but here it goes...
Back when I was at ACA, we served Charlottesville, VA (CHO) but not Charlotte, NC (CLT). One of our not-so-bright gate agents was approached by a pax travelling to CLT. FWIW, our agent was an ESL Speaker (English as a Second Language) I say this not to be racist (which is why I'm not pointing out his nationality) but to illustrate the point that if you're not a fluent English speaker, that given the context of the situation, the two cities may very easily be confused.
Anyway, the young man was approached by the lady, a pax originally ticketed on US (whose gates where just over the bridge in the B concourse, an easy walk). She explained to him that she was going to CLT and that she missed her US flight. He then promptly issued her a ticket for travel to CHO. Apparently, she actually did travel to CHO that day.
What I found pretty hilarious is that he created her a ticket out of NOTHING or for whatever reason never had the appropriate paperwork from US which might have indicuated his mistake.