Originally Posted by Helena Handbaskets
Also, contrary to the advice of some others, I'd stick with driving in Switzerland. If I'm visiting cities, the trains offer some important advantages over driving, but if I'm out to see the countryside, I want to be able to drive up onto mountains that offer good views, into little towns that seem attractive as we discover them, etc.
I happen to agree with this. Driving in Switzerland is easy, and when on a short trip, it provides substantially more flexibility.
I would choose the airport to fly in based on the convenience of flights (out of the US, ZRH would most likely have more options). If you plan to spend some time in the city of your arrival, e.g., ZRH (even if it is just half a day), take a train to the city (cheap, convenient and extremely efficient), leave your luggage in a locker at the main railway station, enjoy your sightseeing without worrying about parking, etc., then rent a car from a downtown location. Besides having less hassle, you'll save some money, as downtown rentals are not subject to airport tax, even if you return your car at the airport location.