Had 6A on a recent flight from HNL to DFW. Not having a window immediately next to me wasn't too much of a deal on an overnight flight arriving at 6 a.m. into DFW (nothing to see at DFW on landing either). But I might feel slightly differently about landing in the Alps on a beautiful morning (depending on sunrise, of course!). That depends on how much you love your window seats.

...but the bigger pain was that if I was reclined in 6A, and the person in 5B had their adjustable headrest "up", I could hardly see the large TV screen at the front of the cabin. Again, I slept most of the way, so it wasn't too bad...but YMMV.