I gave up chasing status in 2018 when I stopped flying 30+ weeks a year after 6 years straight. Before then however, I also flew a lot (100K a year) but, normally nowhere nearly as frequently as I did from 2012-2018.

When is it time to stop ? Don't take this answer as anything but my own situation. When you can afford to pay for international J two or three times a year, and the dates/times/routing is what really matters the most. When you do this you lose allegiance to a carrier or an alliance, as you've exchanged money, instead of points for the seat, so, you've paid for the experience, rather than suffered for it, like I did from 2012-2018.

YMMV obviously.