I have a weeklong stay coming up and currently have The Stratford, Autograph Collection booked. I've been there before, and I generally like that area. My meetings are in Tottenham Court Road, so I'm ~20 mins away on the Elizabeth Line.

I'm no stranger to London, but I always seem to stay east of Hyde Park (Shoreditch, the City, Victoria, Stratford, Canary Wharf). I saw the Marriott Kensington has similar rates, and I've never really stayed in that area. Worth swapping to 'commute' from a different part of London? Seems to have easy access to the Piccadilly line.