Thanksgiving week is great for international travel. If you take the weekend on both ends, it's about 10 days with only 3 PTO days used. Europe is generally free of American tourists but you get cool weather and Christmas markets. Business as usual everywhere else. Great flight availability.
Christmas day is also a very empty day to fly, but isn't as great in Europe where everything is shut down, including public transportation in places.
Asia, however, is festive for Christmas but it's just a regular business day in most places.

Great times to travel and avoid nightmarish family gatherings.