Try AVG free.
I had a pest like this, running as a startup service on my mother in laws computer. I just had her send me the drive.

anyway, you DEFINITLY want to start in safe mode. Get the AVG stuff downloaded, and then installed. I would recommend NO email install, it takes a bit of setup to get right.

Start in SAFE and run the updater, then run it on the system in SAFE and it will find it.

As well, take a look at what the services running are, I found a bunch like smsss.exe, and msa.exe and another one. Do a quick google search and you will see which ones should be deleted.

Delete them and their registry run commands., If you are not happy with registry editing, don't worry about it. Just do a find, delelte the ones that are viruses, hit F3 find again, delete, keep doing that.

Run the AVG again, let it do its thing. Most likely, it will restart.

then, start up again in SAFE mode again and see what AVG and adaware say, no viruses, I think you are clean.

Restart, run in normal mode and check it out again. It is a LOT of do once, do again, do a third time and continue to delete.

Those buggers can wreck havoc.

If you have something in MEMORY, none of these will get it, and you will have to boot with a disc of Norton or MCaffee or something other and run their services at boot.