I have noticed that the hotel in the Ginza area (Edition, AC, Aloft, and Courtyard) have the best access to metro lines. The Ginza and Ginza-itchome stations have 4 lines between them (M, H, G, Y lines) and goes to all key areas of Tokyo.

I stayed at the Edition last year in Ginza and enjoyed it. Will be staying there again in a couple of days time. Also, a number of fine dining restaurants in the area with great bars as well. Its nightlife is upper scale compared to Shibuya, Shinjuku and Roppongi.

I tried to convince myself regarding the mesm which is a fantastic property but the location and metro access would be a problem.

Same thing goes for the Ritz Carlton and Edition Toronamon. I believe its metro access is a little restricted to mac of 2 lines. The Prince Gallery does have great metro access.