I call those pink eyes.

I've done it a few times LAX-IAD. You avoid the worst LA traffic and arrive to an empty beltway.

I avoid true redeyes unless there are cookies and couch at the other end, and so take very few of them for work. When I do take redeyes, I try to stay hydrated during the flight and then get caffeinated as landing approaches. When connecting to places in the midwest where there's the option of a short flight or midcon followed by a longer flight vs a redeye all the way to the east coast and a hop back, I'll take the longer first flight to get more sleep, then get some coffee at the connection and on the second flight.