Depends on the time of day, if your inbound flight is on time, and what terminal & airline you are connecting from/to. If it is on one ticket and you have onward boarding pass, this is doable as long as you are not arriving at peak arrival times for international flights (Global Entry is not so much the problem, it is waiting for your bag - which can take anywhere from 10-30 minutes). You will also have to re clear security (Global Entry speeds things up). Personally I would not do it for any less connection time than 2 hours at EWR, but this is my risk tolerance.