For a tier point run then HBO is the way forward. It depends on how long you are planning to stay at the turnaround location on your run schedule. If it's one or a couple nights then I get by with a rucksack; three to four nights is rucksack and holdall. I would not want to worry about whether my checked bag is going to smoothly make the connections within my outward/return routing - I want to enjoy the experience of lightweight luggage movement.