I remember when the one at Park Meadows opened. The line to get into the parking lot was over a mile long with a dedicated lane in the street. It never took more than 15 minutes to get through the drive through. Have not been to that one in a while. I go to the one in Castle Rock and the lines and wait time have definitely gotten shorter. Qualifier: I only go there for lunch so cannot speak to the dinner experience.
They are building a new one in Parker, much closer to my Daughter's home. It should open this summer.
In-n-Out needs several restaurants to cover the costs of their local warehouses, so there is that to consider. Also, In-n-Out, like any successful business, does their homework before entering into a market. I am sure they know what to expect with each opening.