At risk of getting off topic, I use Advil liqui-gels if I have afternoon migraines. And have you ever noticed these "migraine" versions of OTC medicines? They have the exact same thing as the regular versions but in different packages. Next time you're in the store, look at Excedrin vs. Excedrin Migraine. They both have 250 mg aspirin, 250 mg acetominophen, and 25 mg (?) caffeine. What's the difference, then? Same thing with Advil Migraine vs. Advil Liqui-Gels. Both have the same concentration of solubilized ibuprofen. One is amber and one is blue. I have used both versions of Excedrin and both versions of Advil, and they've both worked the same for me. I usually just buy whichever is less expensive.