Originally Posted by
jetsfan92588
Try to see if you can get the itinerary to price out on ITA Matrix, then you can try to use one of the tools to book that itinerary.
Other than that the only ways I know of to do that are with a travel agent or calling.
Of course, separate reservations is an option as well.
Won't work. OP will need to book on separate tickets. You can book Business in one direction and economy in the other, but you can't mix economy/business hop-by-hop.