Originally Posted by
corporate-wage-slave
The seats are modular, standardised as one unit, and slotted into place. So there isn't anything intrinsically different in terms of one seat versus another. There can be a bit more vibration on 1A due to the connection with the bulkhead. But I really would not overthink this: there are now very few differences between seats, they are all private and it's down to your own preferences over things like proximity or otherwise to the WCs.
The main difference with Row 1 is that because there's (extra) space infront of the seat this is used as a storage area for various service items that the crew need which can be quite noisy and cause disturbance if you're trying to rest. ( This seems to apply to all 4 seats in Row 1 I believe ) .. I would avoid on a night flight at least .. noise from the Galley not really an issue in Row 1 I found .. it's just when they go poking around the side of your seat looking for trays or other things !