I use Backup My PC by Stopm, which was formerly a Veritas Product, which I believe was formerly another product.
It was highly rated by the magazines at the time I was looking, supported just about anything you could backup to, and I did the 30 day trial and didn't have any issues.
Not saying it's better or worse then anything else out there, just that it works.
http://www.stompsoft.com/backupmypc.html