It's even worse when you're traveling in a group, such as a family of 4. If you misconnect, it's nearly impossible to find alternative flights with 4 F seats. For this reason I always try to book long connections (3 or 4 hours) or, if it's really important to make the connecting flight, I sometimes even split the trip with an overnight stay at the hub (for example, the Grand Hyatt DFW).