Originally Posted by Kacee

You'll accrue significantly more UA PQP and miles booking as a UA ticket, and UA in general is much easier to deal with if you need to make a change (I don't know how that compares to what you would accrue crediting to LX Miles & More). From google flights, it appears UA would book you under the LX flight numbers, which is good, you don't want to book the LX flights under UA flight numbers. There used to be an issue with LX not allowing UA ticketed pax into its F lounges, but I believe that's been resolved. You might want to confirm that in the LX forum.

I might also suggest you consider other options in business class for about $10k less, including the UA one-stop via ORD. We recently flew LX F and while it was nice, it is a cut below the world's best F products, and the ground experience at ZRH on the outbound (where you will be taken to the A lounge, rather than the much nicer E lounge) leaves something to be desired. ORD-ZRH is also a bit short to really enjoy the F product. We did however enjoy the tarmac transfer from the A lounge to our onward departure (FCO) in an AMG S Class.