Originally Posted by
physicsdude
Also avoid booking around when there's a major holiday (i.e within two days before and after Thanksgiving, Christmas, New Year's Day, Memorial Day, etc) and or a break for universities and schools (month of March and first two weeks of April).
These are times to avoid flying, not times to avoid *buying* a ticket. However, if you need to call an airline to book a ticket or complete the purchase, regular business hours during a nonholiday weekday give the best odds for getting a fast, experienced, and competent agent.