Originally Posted by
serpens
With an Eagle Creek bag I have, the axle was not bent (as far as I know) but one end of the shaft was displaced so the wheel didn't align properly. (Thank you, Delta.) I could put the axle back in the correct position and the bag would roll fine if unloaded, but when loaded, the axle would get displaced again. When I read the OP's description, I immediately thought of this.
Yep... sounds pretty much exactly my situation. Last trip I was using that bag; gave my wrist quite a work out. It even hurts thinking about it. Definitely going to take a look and maybe just take it in. Even out of warranty, I'm sure it'll still be cheaper than buying something new. I do like that bag despite its size and such goes completely against my normal mode of carryon only.