I would take a look at the CHS airport wiki, which lists current nonstop destinations on each airline which serves CHS:

https://en.m.wikipedia.org/wiki/Char...tional_Airport

Because of AA's new partnership with JetBlue, crediting AA and B6 flights to AA might make sense for you. And, if you will be renting cars/staying in hotels at your various destinations, those activities could help you achieve status in the AAdvantage program relatively quickly -- as would spending on a qualifying AA credit card.

If you're not already familiar with it, have a look at AA's new "Loyalty Points" scheme for attaining status:

https://exploreamerican.com/newaadvantage/