Originally Posted by platbrownguy

Just stay at the PH Milan. Hotel car will cost you money, probably nothing crazy though (maybe 100-150 euro would be my guess, yes more than public transport but worth it IMO for the arrival). Take the train (one transfer required) if you're feeling thrifty.

The hotel is perfectly pleasant and very well located if you only have one night in Milan. Go to the rooftop at the Duomo, enjoy the view, then hit the whirlpool at the spa. No fancy manicure required but why not treat yourself anyhow.