My wife and I are wanting to go to Vegas for about 3 nights in August. I have the AMEX trifecta so looking to use my membership rewards points to fly and also book the hotels within the Fine Hotels and Resorts program. Any ideas of the best way to fly from Southeast Iowa to Vegas using only points? Transfer partners?

Distance from these airports:

DSM: 1 hour
OMA: 3 hours
MCI: 3.5 hours
MSP: 4 hours
ORD: 5 hours

Im willing to drive a bit if the deal is good enough.