Definitely not something I'd consider a non-substantive issue. This is a major downgrade the current configuration for both the A350 and A330 aircraft. DL continues to market the impacted routes as D1 suites and direct aisle access for all international D1 yet that is no longer the case.
I certainly wouldn't be happy to have previously booked a D1 flight on the 333 and find out it was changed to this configuration and loose direct aisle access and privacy. Or, pax who paid for PS are downgraded to a C+ seat.