You don't get separation anxiety? I know for me, the first few hours where I can't connect to corporate email I'm already feeling it (I've gotten better over the years). I always make sure that my boss and close teammates can contact me while I'm overseas in an emergency (there's ALWAYS some knowledge that wasn't handed over to your backup)... I'd say 99% of the time they don't bother me, but (for me at least) it makes me feel better that I can be reached if absolutely required.